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Issue 12, 2011
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Minisci reactions: Versatile CH-functionalizations for medicinal chemists

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Abstract

The addition of a radical to a heteroaromatic base is commonly referred to as a Minsici reaction. Such reactions constitute a broad-set of selective CH-functionalization processes. This review describes some of the major applications of Minisci reactions and related processes to medicinal or biological chemistry, and highlights some potential developments within this area.

Graphical abstract: Minisci reactions: Versatile CH-functionalizations for medicinal chemists

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Article information


Submitted
24 May 2011
Accepted
03 Jul 2011
First published
22 Aug 2011

Med. Chem. Commun., 2011,2, 1135-1161
Article type
Review Article

Minisci reactions: Versatile CH-functionalizations for medicinal chemists

M. A. J. Duncton, Med. Chem. Commun., 2011, 2, 1135
DOI: 10.1039/C1MD00134E

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