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Issue 8, 2011
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Site-selective labeling at Cys302 of aldehyde dehydrogenase unveils a selective mitochondrial stain†

Yun Kyung Kim,a   Jin Kak Lee,b   Jun-Seok Lee,c   Chang No Yoonc  and  Young-Tae Chang*de  
Author affiliations

* Corresponding authors

a Korea Institute of Science and Technology (KIST), Brain Science Institute, Center for Neuro-medicine, Seoul 136-791, South Korea

b Nanormics Inc., 10-57 Hawolgokdong, Seoul 136-865, South Korea

c Korea Institute of Science and Technology (KIST), Future Convergence Research Division, Biomolecules Function Reasearch Center, Seoul 136-791, South Korea

d Lab of Bioimaging Probe Development, Singapore Bioimaging Consortium, Agency for Science, Technology and Research (A*STAR), 11 Biopolis Way, Singapore

e Department of Chemistry & Med Chem Program, Life Sciences Institute, National University of Singapore, 3 Science Drive 3, Singapore, Singapore
E-mail: chmcyt@nus.edu.sg
Fax: +65 6779-1691
Tel: +65 6516-6774

Abstract

A mitochondria-trackable fluorophore, CDy2, selectively labels Cys302 in the active site of mitochondrial aldehyde dehydrogenase (ALDH2).

Graphical abstract: Site-selective labeling at Cys302 of aldehyde dehydrogenase unveils a selective mitochondrial stain

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Supplementary files

Article information

Submitted
07 Apr 2011
Accepted
25 May 2011
First published
09 Jun 2011
Mol. BioSyst., 2011,7, 2375-2378
Article type
Communication
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Site-selective labeling at Cys302 of aldehyde dehydrogenase unveils a selective mitochondrial stain

Y. K. Kim, J. K. Lee, J. Lee, C. N. Yoon and Y. Chang, Mol. BioSyst., 2011, 7, 2375
DOI: 10.1039/C1MB05137G

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