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Issue 12, 2011
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Versatile immunoassays based on isomagnetophoresis

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Abstract

We report an isomagnetophoretic immunoassay capable of detecting an attomolar level of proteins and adjusting the dynamic range of target analytes. Here, the magnetic nanoparticles are used as labels on microbeads in sandwich-type immunoassay, detecting the amount of bound analytes by isomagnetophoretic focusing the solid-support microbeads under the magnetic susceptibility gradient and magnetic field in a microchannel. For the practical purpose, this platform was applied to detect three types of breast cancer biomarkers.

Graphical abstract: Versatile immunoassays based on isomagnetophoresis

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Supplementary files

Article information


Submitted
06 Nov 2010
Accepted
26 Apr 2011
First published
13 May 2011

Lab Chip, 2011,11, 2045-2048
Article type
Communication

Versatile immunoassays based on isomagnetophoresis

Y. K. Hahn and J. Park, Lab Chip, 2011, 11, 2045
DOI: 10.1039/C0LC00569J

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