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Issue 12, 2011
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An efficient and expeditious Fmoc protection of amines and amino acids in aqueous media

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Abstract

A new and environmentally friendly Fmoc protection of a variety of aliphatic and aromatic amines, amino acids, amino alcohols and amino phenols is reported in aqueous media under mild and catalyst-free conditions. The reaction proved to be chemoselective in presence of ambident nucleophiles.

Graphical abstract: An efficient and expeditious Fmoc protection of amines and amino acids in aqueous media

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Publication details

The article was received on 18 Jul 2011, accepted on 23 Sep 2011 and first published on 17 Oct 2011


Article type: Communication
DOI: 10.1039/C1GC15868F
Green Chem., 2011,13, 3355-3359

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    An efficient and expeditious Fmoc protection of amines and amino acids in aqueous media

    M. B. Gawande and P. S. Branco, Green Chem., 2011, 13, 3355
    DOI: 10.1039/C1GC15868F

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