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Issue 11, 2011
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Utilising hardly-water soluble substrates as a second phase enables the straightforward synthesis of chiral alcohols

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Abstract

So far, the alcohol dehydrogenase-catalysed conversion of longer chain aliphatic substrates has been challenging due to their low solubility in aqueous solution. However, by utilising the ketone directly as a second organic phase, the straightforward synthesis of long chain aliphatic chiral alcohols is enabled.

Graphical abstract: Utilising hardly-water soluble substrates as a second phase enables the straightforward synthesis of chiral alcohols

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Publication details

The article was received on 10 Jul 2011, accepted on 19 Aug 2011 and first published on 28 Sep 2011


Article type: Communication
DOI: 10.1039/C1GC15823F
Green Chem., 2011,13, 3093-3095

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    Utilising hardly-water soluble substrates as a second phase enables the straightforward synthesis of chiral alcohols

    C. Kohlmann, N. Robertz, S. Leuchs, L. Greiner and S. Na’amnieh, Green Chem., 2011, 13, 3093
    DOI: 10.1039/C1GC15823F

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