Jump to main content
Jump to site search

Issue 6, 2011
Previous Article Next Article

Dual functional ionic liquids as plasticisers and antimicrobial agents for medical polymers

Author affiliations

Abstract

Contamination of medical devices with bacteria such as Meticillin resistant Staphylococcus aureus (MRSA) is of great clinical concern. Poly(vinyl chloride) is widely used in the production of medical devices, such as catheters. The flexibility of catheter tubing is derived from the addition of plasticisers. Here, we report the design of two dual functional ionic liquids, 1-ethylpyridinium docusate and tributyl(2-hydroxyethyl)phosphonium docusate, which uniquely provide a plasticising effect, and exhibit antimicrobial and antibiofilm-forming activity to a range of antibiotic resistant bacteria. The plasticisation of poly(vinyl chloride) was tailored as a function of ionic liquid concentration. The effective antimicrobial behaviour of both ionic liquids originates from the chemical structure of the anion or cation and is not limited to the length of the alkyl chain on the anion/cation. The design approach adopted will be useful in developing ionic liquids as multi-functional additives for polymers.

Graphical abstract: Dual functional ionic liquids as plasticisers and antimicrobial agents for medical polymers

Back to tab navigation

Supplementary files

Publication details

The article was received on 02 Feb 2011, accepted on 09 Mar 2011 and first published on 11 Apr 2011


Article type: Paper
DOI: 10.1039/C1GC15132K
Green Chem., 2011,13, 1527-1535

  •   Request permissions

    Dual functional ionic liquids as plasticisers and antimicrobial agents for medical polymers

    S. Y. Choi, H. Rodríguez, A. Mirjafari, D. F. Gilpin, S. McGrath, K. R. Malcolm, M. M. Tunney, R. D. Rogers and T. McNally, Green Chem., 2011, 13, 1527
    DOI: 10.1039/C1GC15132K

Search articles by author

Spotlight

Advertisements