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Issue 12, 2011
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Nucleic acid amphiphiles: synthesis and self-assembled nanostructures

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Abstract

This review provides an overview of a relatively new class of bio-conjugates, DNA amphiphiles, which consist of oligonucleotides covalently bonded to synthetic hydrophobic units. The reader will find the basic principles for the structural design and preparation methods of the materials. Moreover, the self-assembly into superstructures of higher order will be highlighted. Finally, some potential applications will be described.

Graphical abstract: Nucleic acid amphiphiles: synthesis and self-assembled nanostructures

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Article information


Submitted
24 May 2011
First published
22 Aug 2011

Chem. Soc. Rev., 2011,40, 5745-5755
Article type
Tutorial Review

Nucleic acid amphiphiles: synthesis and self-assembled nanostructures

M. Kwak and A. Herrmann, Chem. Soc. Rev., 2011, 40, 5745
DOI: 10.1039/C1CS15138J

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