Jump to main content
Jump to site search

Issue 10, 2011
Previous Article Next Article

Decarboxylative coupling reactions: a modern strategy for C–C-bond formation

Author affiliations

Abstract

This critical review examines transition metal-catalyzed decarboxylative couplings that have emerged within recent years as a powerful strategy to form carboncarbon or carbon–heteroatom bonds starting from carboxylic acids. In these reactions, C–C bonds to carboxylate groups are cleaved, and in their place, new carboncarbon bonds are formed. Decarboxylative cross-couplings constitute advantageous alternatives to traditional cross-coupling or addition reactions involving preformed organometallic reagents. Decarboxylative reaction variants are also known for Heck reactions, direct arylation processes, and carbon–heteroatom bond forming reactions.

Graphical abstract: Decarboxylative coupling reactions: a modern strategy for C–C-bond formation

Back to tab navigation

Publication details

The article was received on 06 Apr 2011 and first published on 27 Jul 2011


Article type: Critical Review
DOI: 10.1039/C1CS15093F
Chem. Soc. Rev., 2011,40, 5030-5048

  •   Request permissions

    Decarboxylative coupling reactions: a modern strategy for C–C-bond formation

    N. Rodríguez and L. J. Goossen, Chem. Soc. Rev., 2011, 40, 5030
    DOI: 10.1039/C1CS15093F

Search articles by author

Spotlight

Advertisements