Jump to main content
Jump to site search

Issue 7, 2011
Previous Article Next Article

Beating cancer in multiple ways using nanogold

Author affiliations


Gold nanoparticles possess a unique combination of properties which allow them to act as highly multifunctional anti-cancer agents (X. H. Huang, P. K. Jain, I. H. El-Sayed and M. A. El-Sayed, Nanomedicine, 2007, 2, 681–693; P. Ghosh, G. Han, M. De, C. K. Kim and V. M. Rotello, Adv. Drug Delivery Rev., 2008, 60, 1307–1315; S. Lal, S. E. Clare and N. J. Halas, Acc. Chem. Res., 2008, 41, 1842–1851; D. A. Giljohann, D. S. Seferos, W. L. Daniel, M. D. Massich, P. C. Patel and C. A. Mirkin, Angew. Chem., Int. Ed., 2010, 49, 3280–3294). Not only can they be used as targeted contrast agents for photothermal cancer therapy, they can serve as scaffolds for increasingly potent cancer drug delivery, as transfection agents for selective gene therapy, and as intrinsic antineoplastic agents. This tutorial review will highlight some of the many forms and recent applications of these gold nanoparticle conjugates by our lab and others, as well as their rational design and physiologic interactions.

Graphical abstract: Beating cancer in multiple ways using nanogold

Back to tab navigation

Article information

12 Nov 2010
First published
31 May 2011

Chem. Soc. Rev., 2011,40, 3391-3404
Article type
Tutorial Review

Beating cancer in multiple ways using nanogold

E. C. Dreaden, M. A. Mackey, X. Huang, B. Kang and M. A. El-Sayed, Chem. Soc. Rev., 2011, 40, 3391
DOI: 10.1039/C0CS00180E

Social activity

Search articles by author