Jump to main content
Jump to site search

Issue 9, 2011
Previous Article Next Article

Optical methods for sensing glucose

Author affiliations


This critical review covers the present state of the art in optical sensing of glucose. Following an introduction into the significance of (continuous) sensing of glucose and a brief look back, we discuss methods based on (a) monitoring the optical properties of intrinsically fluorescent or labeled enzymes, their co-enzymes and co-substrates; (b) the measurement of the products of enzymatic oxidation of glucose by glucose oxidase; (c) the use of synthetic boronic acids; (d) the use of Concanavalin A; and (e) the application of other glucose-binding proteins. We finally present an assessment in terms of the advantages and disadvantages of the various methods (237 references).

Graphical abstract: Optical methods for sensing glucose

Back to tab navigation

Publication details

The article was received on 05 Mar 2011 and first published on 14 Jun 2011

Article type: Critical Review
DOI: 10.1039/C1CS15063D
Chem. Soc. Rev., 2011,40, 4805-4839

  •   Request permissions

    Optical methods for sensing glucose

    M. Steiner, A. Duerkop and O. S. Wolfbeis, Chem. Soc. Rev., 2011, 40, 4805
    DOI: 10.1039/C1CS15063D

Search articles by author