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Issue 9, 2011
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Optical methods for sensing glucose

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Abstract

This critical review covers the present state of the art in optical sensing of glucose. Following an introduction into the significance of (continuous) sensing of glucose and a brief look back, we discuss methods based on (a) monitoring the optical properties of intrinsically fluorescent or labeled enzymes, their co-enzymes and co-substrates; (b) the measurement of the products of enzymatic oxidation of glucose by glucose oxidase; (c) the use of synthetic boronic acids; (d) the use of Concanavalin A; and (e) the application of other glucose-binding proteins. We finally present an assessment in terms of the advantages and disadvantages of the various methods (237 references).

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Article information


Submitted
05 Mar 2011
First published
14 Jun 2011

Chem. Soc. Rev., 2011,40, 4805-4839
Article type
Critical Review

Optical methods for sensing glucose

M. Steiner, A. Duerkop and O. S. Wolfbeis, Chem. Soc. Rev., 2011, 40, 4805
DOI: 10.1039/C1CS15063D

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