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Issue 6, 2011
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Fifty-year old samples of progesterone demonstrate the complex role of synthetic impurities in stabilizing a metastable polymorph

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Abstract

We describe a unique experiment whereby analysis of fifty-year old samples of progesterone shows that a metastable, ‘disappearing’ polymorph contains several impurities that are not found in the stable form.

Graphical abstract: Fifty-year old samples of progesterone demonstrate the complex role of synthetic impurities in stabilizing a metastable polymorph

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Supplementary files

Article information


Submitted
16 Nov 2010
Accepted
16 Dec 2010
First published
28 Jan 2011

CrystEngComm, 2011,13, 1775-1777
Article type
Communication

Fifty-year old samples of progesterone demonstrate the complex role of synthetic impurities in stabilizing a metastable polymorph

R. W. Lancaster, L. D. Harris and D. Pearson, CrystEngComm, 2011, 13, 1775
DOI: 10.1039/C0CE00858C

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