Issue 37, 2011
From the journal:

Chemical Communications

Self-assembly of a peptideamphiphile based on hydrolysed Bombyx mori silk fibroin†

Jinming Zhang,a   Ruiwen Hao,a   Lei Huang,a   Jinrong Yao,a   Xin Chena  and  Zhengzhong Shao*a  

* Corresponding authors

a Key Laboratory of Molecular Engineering of Polymers of Ministry of Education, Laboratory of Advanced Materials, Department of Macromolecular Science, Fudan University, Shanghai 200433, China
E-mail: zzshao@fudan.edu.cn

Abstract

An octapeptide, GAGAGAGY, was obtained by a novel method, i.e. hydrolysing Bombyx mori silk fibroin. Afterward, a dodecanoic acid–peptide conjugation was synthesized. This amphiphile assembled into cylindrical nanofibers of planar β-sheets at pH 9 and twisted β-sheets at pH 4.

Graphical abstract: Self-assembly of a peptide amphiphile based on hydrolysed Bombyx mori silk fibroin

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Article information

DOI
https://doi.org/10.1039/C1CC12633D
Article type
Communication
Submitted
05 May 2011
Accepted
01 Aug 2011
First published
22 Aug 2011

Chem. Commun., 2011,47, 10296-10298

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Self-assembly of a peptide amphiphile based on hydrolysed Bombyx mori silk fibroin

J. Zhang, R. Hao, L. Huang, J. Yao, X. Chen and Z. Shao, Chem. Commun., 2011, 47, 10296 DOI: 10.1039/C1CC12633D

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