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Issue 29, 2011
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Solid-phase synthesis of BODIPY dyes and development of an immunoglobulin fluorescent sensor

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Abstract

The diversification of the BODIPY scaffold has been hindered by its controversial adaptability to solid-phase chemistry. Herein we report the first solid-phase synthesis of a BODIPY library in high purities. We screened the library against a set of proteins, identified an immunoglobulin fluorescent sensor (Ig Orange) and confirmed its binding by SPR experiments.

Graphical abstract: Solid-phase synthesis of BODIPY dyes and development of an immunoglobulin fluorescent sensor

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Supplementary files

Article information


Submitted
29 Mar 2011
Accepted
06 Jun 2011
First published
24 Jun 2011

Chem. Commun., 2011,47, 8424-8426
Article type
Communication

Solid-phase synthesis of BODIPY dyes and development of an immunoglobulin fluorescent sensor

M. Vendrell, G. G. Krishna, K. K. Ghosh, D. Zhai, J. Lee, Q. Zhu, Y. H. Yau, S. G. Shochat, H. Kim, J. Chung and Y. Chang, Chem. Commun., 2011, 47, 8424
DOI: 10.1039/C1CC11774B

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