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Issue 21, 2011
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Size-controlled long-circulating PICsome as a ruler to measure critical cut-off disposition size into normal and tumor tissues

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Abstract

Selective disposition of nanocarriers into target tissue is an essential issue in drug delivery. Critical size of nanocarriers (∼150 nm) discriminating the permeability into normal and tumor tissues was determined by the use of size-tunable, polyion complex hollow vesicles (PICsome) as a ruler.

Graphical abstract: Size-controlled long-circulating PICsome as a ruler to measure critical cut-off disposition size into normal and tumor tissues

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Publication details

The article was received on 14 Mar 2011, accepted on 09 Apr 2011 and first published on 26 Apr 2011


Article type: Communication
DOI: 10.1039/C1CC11465D
Chem. Commun., 2011,47, 6054-6056

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    Size-controlled long-circulating PICsome as a ruler to measure critical cut-off disposition size into normal and tumor tissues

    Y. Anraku, A. Kishimura, A. Kobayashi, M. Oba and K. Kataoka, Chem. Commun., 2011, 47, 6054
    DOI: 10.1039/C1CC11465D

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