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Issue 17, 2011
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Real-time, in vivo monitoring and pharmacokinetics of valproic acidvia a novel biomarker in exhaled breath

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Abstract

Extractive electrospray ionization mass spectrometry is shown to allow real-time, in vivodrug monitoring and pharmacokinetic measurement in a non-invasive, pain-free manner as demonstrated by the mass spectral measurement of a novel exhaled breath biomarker for valproic acid, a medication used to control epilepsy.

Graphical abstract: Real-time, in vivo monitoring and pharmacokinetics of valproic acidvia a novel biomarker in exhaled breath

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Article information


Submitted
18 Jan 2011
Accepted
10 Feb 2011
First published
04 Mar 2011

Chem. Commun., 2011,47, 4884-4886
Article type
Communication

Real-time, in vivo monitoring and pharmacokinetics of valproic acidvia a novel biomarker in exhaled breath

G. Gamez, L. Zhu, A. Disko, H. Chen, V. Azov, K. Chingin, G. Krämer and R. Zenobi, Chem. Commun., 2011, 47, 4884
DOI: 10.1039/C1CC10343A

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