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Metastable state silver nanoparticle surface-enhanced Raman scattering has been experimentally and theoretically demonstrated; the signal is two to three orders of magnitude higher than that for the traditional method. Ultrasensitive surface-enhanced Raman scattering signals of illicit drug cocaine and organophosphate pesticide methyl-parathion were observed.

Graphical abstract: Metastable state nanoparticle-enhanced Raman spectroscopy for highly sensitive detection

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