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Issue 10, 2011
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Thermodynamic stability of Hoogsteen and Watson–Crick base pairs in the presence of histone H3-mimicking peptide

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Abstract

We found that Hoogsteen base pairs were stabilized by molecular crowding and a histone H3-mimicking peptide, which was not observed for Watson–Crick base pairs. Our findings demonstrate that the type of DNA base pair is critical for the interaction between DNA and histones.

Graphical abstract: Thermodynamic stability of Hoogsteen and Watson–Crick base pairs in the presence of histone H3-mimicking peptide

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Publication details

The article was received on 24 Dec 2010, accepted on 18 Jan 2011 and first published on 09 Feb 2011


Article type: Communication
DOI: 10.1039/C0CC05776B
Chem. Commun., 2011,47, 2790-2792

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    Thermodynamic stability of Hoogsteen and Watson–Crick base pairs in the presence of histone H3-mimicking peptide

    S. Pramanik, K. Nakamura, K. Usui, S. Nakano, S. Saxena, J. Matsui, D. Miyoshi and N. Sugimoto, Chem. Commun., 2011, 47, 2790
    DOI: 10.1039/C0CC05776B

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