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Issue 33, 2011
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Metal-free intramolecular oxidative decarboxylative amination of primary α-amino acids with product selectivity

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Abstract

A novel metal-free intramolecular oxidative decarboxylative coupling of primary α-amino acids with 2-aminobenzoketones under mild and neutral conditions was developed. Different quinazolines can be selectively obtained by various oxidants.

Graphical abstract: Metal-free intramolecular oxidative decarboxylative amination of primary α-amino acids with product selectivity

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Supplementary files

Article information


Submitted
17 May 2011
Accepted
20 Jun 2011
First published
19 Jul 2011

Chem. Commun., 2011,47, 9513-9515
Article type
Communication

Metal-free intramolecular oxidative decarboxylative amination of primary α-amino acids with product selectivity

Y. Yan and Z. Wang, Chem. Commun., 2011, 47, 9513
DOI: 10.1039/C1CC12885J

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