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Issue 30, 2011
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Self-assembling nanomicelles of a novel camptothecin prodrug engineered with a redox-responsive release mechanism

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Abstract

A novel amphiphilic camptothecin prodrug that spontaneously arranges into nanomicelles which preferentially release the cytotoxic drug under tumor-relevant reductive conditions is designed.

Graphical abstract: Self-assembling nanomicelles of a novel camptothecin prodrug engineered with a redox-responsive release mechanism

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Publication details

The article was received on 28 Apr 2011, accepted on 20 Jun 2011 and first published on 01 Jul 2011


Article type: Communication
DOI: 10.1039/C1CC12495A
Chem. Commun., 2011,47, 8647-8649

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    Self-assembling nanomicelles of a novel camptothecin prodrug engineered with a redox-responsive release mechanism

    X. Li, H. Wen, H. Dong, W. Xue, G. M. Pauletti, X. Cai, W. Xia, D. Shi and Y. Li, Chem. Commun., 2011, 47, 8647
    DOI: 10.1039/C1CC12495A

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