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Issue 26, 2011
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DNA diagnostics with a bacterial reporter probe

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Abstract

A DNA diagnostic system has been developed by using a bacterial reporter probe. DNA hybridization-driven magnetic isolation of E. coli, followed by exponential bacterial growth and fluorescent protein expression, allows the translation of a target binding event into a vastly amplified signal and a highly sensitive/selective detection platform.

Graphical abstract: DNA diagnostics with a bacterial reporter probe

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Supplementary files

Article information


Submitted
16 Mar 2011
Accepted
15 Apr 2011
First published
03 May 2011

Chem. Commun., 2011,47, 7470-7472
Article type
Communication

DNA diagnostics with a bacterial reporter probe

Y. Yan, W. Sha, J. Sun, X. Shu, S. Sun and J. Zhu, Chem. Commun., 2011, 47, 7470 DOI: 10.1039/C1CC11515D

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