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Issue 18, 2011
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Expanding the dynamic measurement range for polymeric nanoparticle pH sensors

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Abstract

Conventional optical nanoparticle pH sensors that are designed for ratiometric measurements in cells have been based on utilizing one sensor fluorophore and one reference fluorophore in each nanoparticle, which results in a relatively narrow dynamic measurement range. This results in substantial challenges when conducting live cell measurements, which often leads to misleading results. In the present work we provide a simple solution to this problem.

Graphical abstract: Expanding the dynamic measurement range for polymeric nanoparticle pH sensors

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Supplementary files

Article information


Submitted
22 Jan 2011
Accepted
15 Mar 2011
First published
30 Mar 2011

Chem. Commun., 2011,47, 5268-5270
Article type
Communication

Expanding the dynamic measurement range for polymeric nanoparticle pH sensors

H. Sun, K. Almdal and T. L. Andresen, Chem. Commun., 2011, 47, 5268 DOI: 10.1039/C1CC10439J

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