Issue 10, 2011

Bio-functionalization of metal–organic frameworks by covalent protein conjugation

Abstract

Bioconjugation of functional proteins onto metal–organic frameworks (MOFs) has been achieved using activation of pendent linking groups of the organic linkers on the surface of MOFs. Fluorescent microscopy revealed successful conjugation of an enhanced fluorescent protein onto MOFs. In addition, Candida-antarctica-lipase-B-conjugated MOFs showed no loss of enantioselectivity and activity in transesterification of (±)-1-phenylethanol.

Graphical abstract: Bio-functionalization of metal–organic frameworks by covalent protein conjugation

Supplementary files

Article information

Article type
Communication
Submitted
16 Aug 2010
Accepted
17 Dec 2010
First published
17 Jan 2011

Chem. Commun., 2011,47, 2904-2906

Bio-functionalization of metal–organic frameworks by covalent protein conjugation

S. Jung, Y. Kim, S. Kim, T. Kwon, S. Huh and S. Park, Chem. Commun., 2011, 47, 2904 DOI: 10.1039/C0CC03288C

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