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Issue 1, 2011
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Isothermal detection of RNA with restriction endonucleases

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Abstract

Herein, we demonstrate how to detect nucleic acids that do not contain restriction endonuclease recognition sites with restriction endonucleases. We show that the topology of DNA probes used in this detection strategy remarkably affects the efficiency of RNA/DNA detection.

Graphical abstract: Isothermal detection of RNA with restriction endonucleases

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Supplementary files

Article information


Submitted
29 Jun 2010
Accepted
13 Sep 2010
First published
01 Oct 2010

Chem. Commun., 2011,47, 200-202
Article type
Communication

Isothermal detection of RNA with restriction endonucleases

L. Yan, S. Nakayama, S. Yitbarek, I. Greenfield and H. O. Sintim, Chem. Commun., 2011, 47, 200 DOI: 10.1039/C0CC02208J

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