Jump to main content
Jump to site search

Issue 1, 2011
Previous Article Next Article

The pattern recognition molecule deleted in malignant brain tumors 1 (DMBT1) and synthetic mimics inhibit liposomal nucleic acid delivery

Author affiliations

Abstract

Liposomal nucleic acid delivery is a preferred option for therapeutic settings. The cellular pattern recognition molecule DMBT1, secreted at high levels in various diseases, and synthetic mimics efficiently inhibit liposomal nucleic acid delivery to human cells. These findings may have relevance for therapeutic nucleic acid delivery strategies.

Graphical abstract: The pattern recognition molecule deleted in malignant brain tumors 1 (DMBT1) and synthetic mimics inhibit liposomal nucleic acid delivery

Back to tab navigation

Publication details

The article was received on 29 Jun 2010, accepted on 18 Aug 2010 and first published on 07 Sep 2010


Article type: Communication
DOI: 10.1039/C0CC02186E
Chem. Commun., 2011,47, 188-190

  •   Request permissions

    The pattern recognition molecule deleted in malignant brain tumors 1 (DMBT1) and synthetic mimics inhibit liposomal nucleic acid delivery

    P. Lund Hansen, S. Blaich, C. End, S. Schmidt, J. B. Moeller, U. Holmskov and J. Mollenhauer, Chem. Commun., 2011, 47, 188
    DOI: 10.1039/C0CC02186E

Search articles by author

Spotlight

Advertisements