Issue 10, 2010
From the journal:

Soft Matter

Tuning hydrogel properties and function using substituent effects†

Richie E. Kohman,bc   Chaenyung Cha,bc   Steven C. Zimmermanc  and  Hyunjoon Kong*ab  

* Corresponding authors

a Department of Chemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign, 600 S. Mathews Avenue, Urbana, IL, USA
E-mail: hjkong06@illinois.edu
Fax: (+1) 217-333-5052

b Institute for Genomic Biology, University of Illinois at Urbana-Champaign, 1206 W. Gregory Drive, Urbana, IL, USA

c Department of Chemistry, University of Illinois at Urbana-Champaign, 600 S. Mathews Avenue, Urbana, IL, USA

Abstract

The physical properties and function of hydrogels are shown to depend on the substituents present in three novel 1,3,5-triazaadamantane (TAA) cross-linkers. Gel stiffness and degradation rate at varied pHs could be predictably tuned with the cross-linker substituents used to form the gel. Subsequently, protein release from the hydrogel were controlled with chemical structure of the cross-linker.

Graphical abstract: Tuning hydrogel properties and function using substituent effects

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Article information

DOI
https://doi.org/10.1039/C001548B
Article type
Communication
Submitted
25 Jan 2010
Accepted
23 Mar 2010
First published
09 Apr 2010

Soft Matter, 2010,6, 2150-2152

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Tuning hydrogel properties and function using substituent effects

R. E. Kohman, C. Cha, S. C. Zimmerman and H. Kong, Soft Matter, 2010, 6, 2150 DOI: 10.1039/C001548B

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