Jump to main content
Jump to site search

Issue 5, 2010
Previous Article Next Article

Colloidal phytosterols: synthesis, characterization and bioaccessibility

Author affiliations

Abstract

We demonstrate the synthesis of phytosterol colloidal particles using a simple food grade method based on antisolvent precipitation in the presence of a non-ionic surfactant. The resulting colloidal particles have a rod-like shape with some degree of crystallinity. The colloidal dispersions display good stability assured by surface charge, due to the presence of water and hydroxyl groups on the particle surface, and by steric stabilisation, due to the presence of a non-ionic stabiliser. In vitro bioaccessibility experiments demonstrated that colloidal phytosterol can be effectively solubilised in model dietary mixed micelles and the micellar cholesterol concentration can be effectively reduced by 47% within two hours.

Graphical abstract: Colloidal phytosterols: synthesis, characterization and bioaccessibility

Back to tab navigation

Article information


Submitted
10 Jun 2009
Accepted
18 Nov 2009
First published
24 Dec 2009

Soft Matter, 2010,6, 928-936
Article type
Paper

Colloidal phytosterols: synthesis, characterization and bioaccessibility

L. Rossi, J. W. M. Seijen ten Hoorn, S. M. Melnikov and K. P. Velikov, Soft Matter, 2010, 6, 928
DOI: 10.1039/B911371A

Social activity

Search articles by author

Spotlight

Advertisements