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Issue 1, 2010
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Cell surface-based differentiation of cell types and cancer states using a gold nanoparticle-GFP based sensing array

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Abstract

Gold nanoparticle-green fluorescent protein (NP-GFP) based arrays have been created for rapid identification of mammalian cells on the basis of cell surface properties. Highly reproducible characteristic patterns were obtained from different cell types enabling the identification of cell types and cancer states. Using these arrays we could differentiate between isogenic normal, cancer and metastatic cell types using only ∼5000 cells.

Graphical abstract: Cell surface-based differentiation of cell types and cancer states using a gold nanoparticle-GFP based sensing array

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Publication details

The article was received on 03 Feb 2010, accepted on 29 Mar 2010 and first published on 24 May 2010


Article type: Edge Article
DOI: 10.1039/C0SC00165A
Citation: Chem. Sci., 2010,1, 134-138

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    Cell surface-based differentiation of cell types and cancer states using a gold nanoparticle-GFP based sensing array

    A. Bajaj, S. Rana, O. R. Miranda, J. C. Yawe, D. J. Jerry, U. H. F. Bunz and V. M. Rotello, Chem. Sci., 2010, 1, 134
    DOI: 10.1039/C0SC00165A

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