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Abstract | Cited by

We present an efficient method to synthesize three new asymmetric trimethine cyanine dyes containing only one carboxylic acid group for bioconjugation. Two of them have better protein labeling performance than other conventional cyanine dyes due to their particular structure design.

Graphical abstract: Asymmetric trimethine 3H-indocyanine dyes: efficient synthesis and protein labeling

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