Synthesis of C-6-substituted uridine phosphonates through aerobic ligand-free Suzuki–Miyaura cross-coupling†‡
Abstract
An efficient protocol for the construction of C-6-(hetero)aryl-substituted
* Corresponding authors
a
Laboratory for Medicinal Chemistry, Faculty of Pharmaceutical Sciences (FFW), Ghent University, Harelbekestraat 72, Ghent, Belgium
E-mail:
serge.vancalenbergh@ugent.be
Fax: +32 9 2648146
Tel: +32 9 2648124
b
Centre for New Antivirals and Antineoplastics, Institute of Organic Chemistry and Biochemistry Academy of Sciences of the Czech Republic, v.v.i.(IOCB), Gilead & IOCB Research Center, Prague 6, Czech Republic
E-mail:
nencka@uochb.cas.cz
Fax: +420 220183560
Tel: +420 220183323
c
NMR and Structure Analysis Unit, Department of Organic Chemistry, Ghent University, Krijgslaan 281 S4, Ghent, Belgium
E-mail:
jose.martins@ugent.be
Fax: +32 9 2644972
An efficient protocol for the construction of C-6-(hetero)aryl-substituted
R. Nencka, D. Sinnaeve, I. Karalic, J. C. Martins and S. Van Calenbergh, Org. Biomol. Chem., 2010, 8, 5234 DOI: 10.1039/C0OB00061B
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