Jump to main content
Jump to site search

Issue 11, 2010
Previous Article Next Article

An efficient entry to 1,2-benzisoxazoles via 1,3-dipolar cycloaddition of in situ generated nitrile oxides and benzyne

Author affiliations

Abstract

An efficient protocol for the synthesis of a range of 1,2-benzisoxazoles using an improved 1,3-dipolar cycloaddition of nitrile oxides and benzyne is described. Key to the procedure is the in situ generation of the reactive nitrile oxide and benzyne reactants simultaneously.

Graphical abstract: An efficient entry to 1,2-benzisoxazoles via 1,3-dipolar cycloaddition of in situ generated nitrile oxides and benzyne

Back to tab navigation

Supplementary files

Publication details

The article was received on 05 Jan 2010, accepted on 09 Mar 2010 and first published on 07 Apr 2010


Article type: Paper
DOI: 10.1039/B927235F
Org. Biomol. Chem., 2010,8, 2537-2542

  •   Request permissions

    An efficient entry to 1,2-benzisoxazoles via 1,3-dipolar cycloaddition of in situ generated nitrile oxides and benzyne

    C. Spiteri, C. Mason, F. Zhang, D. J. Ritson, P. Sharma, S. Keeling and J. E. Moses, Org. Biomol. Chem., 2010, 8, 2537
    DOI: 10.1039/B927235F

Search articles by author

Spotlight

Advertisements