Issue 9, 2010
From the journal:

Organic & Biomolecular Chemistry

Continuous flow processing from microreactors to mesoscale: the Bohlmann–Rahtz cyclodehydration reaction†‡

Mark C. Bagley,*a   Vincenzo Fusillo,a   Robert L. Jenkins,a   M. Caterina Lubinua  and  Christopher Masonb  

* Corresponding authors

a School of Chemistry, Main Building, Cardiff University, Park Place, Cardiff, UK
E-mail: Bagleymc@cardiff.ac.uk
Fax: +44 29 2087 4030
Tel: +44 29 2087 4029

b CEM (Microwave Technology) Ltd, 2 Middle Slade, Buckingham, UK
Fax: +44 29 1280 822342
Tel: +44 1280 822873

Abstract

The cyclodehydration of a number of Bohlmann–Rahtz aminodienones exemplifies the use of continuous flow processing to transfer operations from commercial microreactors and microwave batch reactors to mesoscale production using different technology platforms, including a microwave flow reactor.

Graphical abstract: Continuous flow processing from microreactors to mesoscale: the Bohlmann–Rahtz cyclodehydration reaction

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Article information

DOI
https://doi.org/10.1039/B926387J
Article type
Paper
Submitted
16 Dec 2009
Accepted
25 Feb 2010
First published
11 Mar 2010

Org. Biomol. Chem., 2010,8, 2245-2251

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Continuous flow processing from microreactors to mesoscale: the Bohlmann–Rahtz cyclodehydration reaction

M. C. Bagley, V. Fusillo, R. L. Jenkins, M. C. Lubinu and C. Mason, Org. Biomol. Chem., 2010, 8, 2245 DOI: 10.1039/B926387J

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