Issue 12, 2010
From the journal:

Nanoscale

Paramagnetic nanofibrous composite films enhance the osteogenic responses of pre-osteoblastcells†

Jie Meng,‡a   Yu Zhang,‡b   Xiaojin Qi,a   Hua Kong,a   Chaoying Wang,c   Zhen Xu,a   Sishen Xie,c   Ning Gu*b  and  Haiyan Xu*a  

* Corresponding authors

a Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China
E-mail: xuhy@pumc.edu.cn

b Southeastern University, Nanjing, China
E-mail: guning@seu.edu.cn

c Institute of Physics, Chinese Academy of Sciences, Beijing, China

Abstract

In this work, a paramagnetic nanofibrous composite film was fabricated with poly lactide, hydroxyapatite and γ-Fe203 nanoparticles using the electrospinning technique. The composite film significantly enhanced the proliferation, differentiation and ECM secretion of the osteoblast cells under a static magnetic field, which offers promising application potentials in bone tissue engineering and bone regeneration therapy.

Graphical abstract: Paramagnetic nanofibrous composite films enhance the osteogenic responses of pre-osteoblast cells

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Article information

DOI
https://doi.org/10.1039/C0NR00178C
Article type
Communication
Submitted
09 Mar 2010
Accepted
01 Sep 2010
First published
15 Oct 2010

Nanoscale, 2010,2, 2565-2569

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Paramagnetic nanofibrous composite films enhance the osteogenic responses of pre-osteoblast cells

J. Meng, Y. Zhang, X. Qi, H. Kong, C. Wang, Z. Xu, S. Xie, N. Gu and H. Xu, Nanoscale, 2010, 2, 2565 DOI: 10.1039/C0NR00178C

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