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Covering: up to the end of 2008

This review discusses the biosynthesis of natural products that are generated by trans-AT polyketide synthases, a family of catalytically versatile enzymes that have recently been recognized as one of the major group of proteins involved in the production of bioactive polyketides. 436 references are cited

Graphical abstract: Biosynthesis of polyketides by trans-AT polyketide synthases

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