Issue 4, 2010
From the journal:

Molecular BioSystems

Solubilization of membraneproteins with novel N-acylamino aciddetergents†

Ryota Abe,a   Jose M. M. Caaveiro,a   Motonori Kudoua  and  Kouhei Tsumoto*a  

* Corresponding authors

a Department of Medical Genome Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Japan
E-mail: tsumoto@k.u-tokyo.ac.jp
Fax: +81-4-7136-3601
Tel: +81-4-7136-3600

Abstract

N-Acylamino acids are a new family of versatile biological surfactants capable of extracting integral membrane proteins of various topologies from the biological membrane, in many instances surpassing the efficiency of commercial detergents.

Graphical abstract: Solubilization of membrane proteins with novel N-acylamino acid detergents

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Article information

DOI
https://doi.org/10.1039/B925791H
Article type
Communication
Submitted
07 Dec 2009
Accepted
18 Jan 2010
First published
16 Feb 2010

Mol. BioSyst., 2010,6, 677-679

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Solubilization of membrane proteins with novel N-acylamino acid detergents

R. Abe, J. M. M. Caaveiro, M. Kudou and K. Tsumoto, Mol. BioSyst., 2010, 6, 677 DOI: 10.1039/B925791H

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