Solvent-free synthesis of 1,4-disubstituted 1,2,3-triazoles using a low amount of Cu(PPh3)2NO3 complex

Dong Wang; Na Li; Mingming Zhao; Weilin Shi; Chaowei Ma; Baohua Chen

doi:10.1039/C0GC00381F

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Solvent-free synthesis of 1,4-disubstituted 1,2,3-triazoles using a low amount of Cu(PPh₃)₂NO₃ complex†

Dong Wang,^ab Na Li,^ab Mingming Zhao,^ab Weilin Shi,^ab Chaowei Ma^ab and Baohua Chen*^ab

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* Corresponding authors

^a State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou, P. R. of China
E-mail: chbh@lzu.edu.cn

^b Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu Province, Lanzhou, P. R. of China

Abstract

We have developed an environmentally friendly and highly efficient method for copper-catalyzed cycloaddition of organic azides and terminal alkynes under solvent-free conditions. The protocol uses the cheap and easy-to-prepare Cu(PPh₃)₂NO₃ complex as the catalyst.

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Article information

DOI: https://doi.org/10.1039/C0GC00381F
Article type: Communication
Submitted: 01 Aug 2010
Accepted: 24 Sep 2010
First published: 13 Oct 2010

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Green Chem., 2010,12, 2120-2123

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Solvent-free synthesis of 1,4-disubstituted 1,2,3-triazoles using a low amount of Cu(PPh₃)₂NO₃ complex

D. Wang, N. Li, M. Zhao, W. Shi, C. Ma and B. Chen, Green Chem., 2010, 12, 2120 DOI: 10.1039/C0GC00381F

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