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Issue 10, 2010
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Heterogeneous catalytic synthesis using microreactor technology

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The application of heterogeneous catalysis in conjunction with microreactor technology can facilitate a cleaner and scalable flow methodology for organic synthesis. In this tutorial review we present recent advances in the design of supported catalysts for emerging synthetic applications within microreactor technology. Specifically, transition metal catalysts such as palladium, copper, ruthenium, and nickel are described on silica, monolithic, magnetic nanoparticles and polymer supports. These catalysts have been utilised to promote a range of reactions including Heck, Sonogashira, Suzuki, Kumada, olefin metathesis, hydrogenation and benzannulation reactions.

Graphical abstract: Heterogeneous catalytic synthesis using microreactor technology

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Article information

21 May 2010
20 Jul 2010
First published
17 Sep 2010

Green Chem., 2010,12, 1687-1703
Article type
Tutorial Review

Heterogeneous catalytic synthesis using microreactor technology

C. G. Frost and L. Mutton, Green Chem., 2010, 12, 1687
DOI: 10.1039/C0GC00133C

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