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Issue 8, 2010
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Multiple fluorescent chemical sensing and imaging

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Optical sensors, unlike most others, enable multiple sensing of (bio)chemical species by making use of probes whose signals can be differentiated by spectral and/or temporal resolution. Multiple sensors are of substantial interest for continuous monitoring of chemical parameters in complex samples such as blood, bioreactor fluids, in the chemical industry, aerodynamic research, and when monitoring food quality control, to mention typical examples. Moreover, such sensors enable non-invasive, non-toxic and online detection. We discuss in this critical review the state of the art in terms of spectroscopic principles, materials (mainly indicator probes and polymers), and give selected examples for dual and triple sensors along with a look into the future (109 references).

Graphical abstract: Multiple fluorescent chemical sensing and imaging

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Article information

04 Nov 2009
First published
22 Jun 2010

Chem. Soc. Rev., 2010,39, 3102-3114
Article type
Critical Review

Multiple fluorescent chemical sensing and imaging

M. I. J. Stich, L. H. Fischer and O. S. Wolfbeis, Chem. Soc. Rev., 2010, 39, 3102
DOI: 10.1039/B909635N

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