Jump to main content
Jump to site search

Issue 2, 2010
Previous Article Next Article

Intermolecular oxidative cross-coupling of arenes

Author affiliations


Biaryls constitute an important subunit found in medicinal agents, functional materials, and natural products. While the Suzuki reaction and related processes currently represent the method of choice for the construction of arenearene bonds, the direct-coupling of two unfunctionalized arenes mediated by the addition of an oxidant represents a powerful alternative strategy for biaryl synthesis. This tutorial review describes recent progress in this rapidly developing field, focusing on intermolecular examples of selective arene oxidation strategies and metal-catalyzed oxidative cross-coupling via C–H activation.

Graphical abstract: Intermolecular oxidative cross-coupling of arenes

Back to tab navigation

Publication details

The article was received on 16 Jun 2009 and first published on 07 Oct 2009

Article type: Tutorial Review
DOI: 10.1039/B907809F
Citation: Chem. Soc. Rev., 2010,39, 540-548

  •   Request permissions

    Intermolecular oxidative cross-coupling of arenes

    J. A. Ashenhurst, Chem. Soc. Rev., 2010, 39, 540
    DOI: 10.1039/B907809F

Search articles by author