Effect of substitution on molecular conformation and packing features in a series of aryl substituted ethyl-6-methyl-4-phenyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylates†
Abstract
The supramolecular structures of eight aryl protected ethyl-6-methyl-4-phenyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylates were analyzed in order to understand the effect of variations in functional C and N–H⋯O
C intermolecular dimers forming a sheet like structure. In addition, weak C–H⋯O and C–H⋯π intermolecular interactions provide additional stability to the crystal packing.