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Issue 45, 2010
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MhyADH catalysed Michael addition of water and in situoxidation

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Abstract

The Michael addition of water is a major challenge. Here an enzymatic approach is described. Interestingly, the enzyme (MhyADH) does not only catalyse the Michael addition of water but also the in situ oxidation of the product.

Graphical abstract: MhyADH catalysed Michael addition of water and in situ oxidation

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Publication details

The article was received on 13 Aug 2010, accepted on 09 Sep 2010 and first published on 27 Sep 2010


Article type: Communication
DOI: 10.1039/C0CC03229H
Chem. Commun., 2010,46, 8588-8590

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    MhyADH catalysed Michael addition of water and in situ oxidation

    J. Jin, P. C. Oskam, S. K. Karmee, A. J. J. Straathof and U. Hanefeld, Chem. Commun., 2010, 46, 8588
    DOI: 10.1039/C0CC03229H

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