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Issue 46, 2010
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O-Glycoligases, a new category of glycoside bond-forming mutant glycosidases, catalyse facile syntheses of isoprimeverosides

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Abstract

A mutant α-xylosidase that lacks its catalytic acid/base residue efficiently catalyses the synthesis of O-linked isoprimeverosides (Xyl-α-1,6GlcOR) in near quantitative yields.

Graphical abstract: O-Glycoligases, a new category of glycoside bond-forming mutant glycosidases, catalyse facile syntheses of isoprimeverosides

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Publication details

The article was received on 11 Aug 2010, accepted on 05 Oct 2010 and first published on 28 Oct 2010


Article type: Communication
DOI: 10.1039/C0CC03168B
Chem. Commun., 2010,46, 8725-8727

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    O-Glycoligases, a new category of glycoside bond-forming mutant glycosidases, catalyse facile syntheses of isoprimeverosides

    Y. Kim, R. Zhang, H. Chen and S. G. Withers, Chem. Commun., 2010, 46, 8725
    DOI: 10.1039/C0CC03168B

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