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Issue 41, 2010
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Structure–activity relationships of the phosphonateantibiotic dehydrophos

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Abstract

Synthetic derivatives of the phosphonate antibiotic dehydrophos were tested for antimicrobial activity. Both the phosphonate monomethyl ester and the vinyl phosphonate moiety proved to be important for bacteriocidal activity of the natural product.

Graphical abstract: Structure–activity relationships of the phosphonate antibiotic dehydrophos

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Publication details

The article was received on 01 Aug 2010, accepted on 02 Sep 2010 and first published on 27 Sep 2010


Article type: Communication
DOI: 10.1039/C0CC02958K
Chem. Commun., 2010,46, 7694-7696

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    Structure–activity relationships of the phosphonate antibiotic dehydrophos

    M. Kuemin and W. A. van der Donk, Chem. Commun., 2010, 46, 7694
    DOI: 10.1039/C0CC02958K

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