Issue 38, 2010

Methylerythritol cyclodiphosphate (MEcPP) in deoxyxylulose phosphate pathway: synthesis from an epoxide and mechanisms

Abstract

In this communication, we reported another unique IspG-catalyzed transformation, the production of its substrate, MEcPP, from (2R,3R)-4-hydroxy-3-methyl-2,3-epoxybutanyl diphosphate (Epoxy-HMBPP) when reductants are excluded from the reaction mixture.

Graphical abstract: Methylerythritol cyclodiphosphate (MEcPP) in deoxyxylulose phosphate pathway: synthesis from an epoxide and mechanisms

Supplementary files

Article information

Article type
Communication
Submitted
15 Jul 2010
Accepted
13 Aug 2010
First published
01 Sep 2010

Chem. Commun., 2010,46, 7220-7222

Methylerythritol cyclodiphosphate (MEcPP) in deoxyxylulose phosphate pathway: synthesis from an epoxide and mechanisms

Y. Xiao, R. L. Nyland II, C. L. F. Meyers and P. Liu, Chem. Commun., 2010, 46, 7220 DOI: 10.1039/C0CC02594A

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