Issue 45, 2010
From the journal:

Chemical Communications

Generation of benzyne from benzoic acid using C–H activation†

Alastair A. Cant,a   Lee Robertsb  and  Michael F. Greaney*a  

* Corresponding authors

a School of Chemistry, University of Edinburgh, King's Buildings, West Mains Rd, Edinburgh, UK
E-mail: Michael.Greaney@ed.ac.uk
Tel: +44(0) 131 6504726

b Discovery Chemistry Pfizer Global R & D, Sandwich CT13 9NJ, UK

Abstract

ortho C–H activation of benzoic acids with Pd(II) generates an oxapalladacycle that can decarboxylate to produce a palladium-associated aryne. The arynes then undergo [2+2+2] trimerisation to afford triphenylenes.

Graphical abstract: Generation of benzyne from benzoic acid using C–H activation

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C0CC02547J
Article type
Communication
Submitted
13 Jul 2010
Accepted
30 Sep 2010
First published
18 Oct 2010

Chem. Commun., 2010,46, 8671-8673

Permissions

Request permissions

Generation of benzyne from benzoic acid using C–H activation

A. A. Cant, L. Roberts and M. F. Greaney, Chem. Commun., 2010, 46, 8671 DOI: 10.1039/C0CC02547J

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements