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Issue 41, 2010
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The evolvability of lead peptides from small library screens

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Abstract

Very little is known about the evolvability of lead peptides that are isolated from small library screens. Here we begin to explore this question by comparing the directed evolution of two peptides previously isolated from a small library screen to new ligands generated de novo by in vitro selection.

Graphical abstract: The evolvability of lead peptides from small library screens

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Publication details

The article was received on 18 May 2010, accepted on 11 Aug 2010 and first published on 09 Sep 2010


Article type: Communication
DOI: 10.1039/C0CC01475C
Citation: Chem. Commun., 2010,46, 7778-7780
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    The evolvability of lead peptides from small library screens

    J. Zhang, B. A. R. Williams, M. T. Nilsson and J. C. Chaput, Chem. Commun., 2010, 46, 7778
    DOI: 10.1039/C0CC01475C

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