Jump to main content
Jump to site search

Issue 34, 2010
Previous Article Next Article

Synthesis of MUC1–lipopeptide chimeras

Author affiliations

Abstract

An efficient method for the convergent assembly of MUC1–lipopeptide vaccine candidates is described. Chimeras consisting of MUC1 glycopeptides (bearing multiple copies of the TN and T tumour-associated carbohydrate antigens) tethered to the lipopeptide immunoadjuvant Pam3CysSer were synthesised in high yields using a fragment-based condensation strategy.

Graphical abstract: Synthesis of MUC1–lipopeptide chimeras

Back to tab navigation

Supplementary files

Publication details

The article was received on 12 May 2010, accepted on 25 Jun 2010 and first published on 28 Jul 2010


Article type: Communication
DOI: 10.1039/C0CC01360A
Citation: Chem. Commun., 2010,46, 6249-6251
  •   Request permissions

    Synthesis of MUC1–lipopeptide chimeras

    B. L. Wilkinson, L. R. Malins, C. K. Y. Chun and R. J. Payne, Chem. Commun., 2010, 46, 6249
    DOI: 10.1039/C0CC01360A

Search articles by author

Spotlight

Advertisements