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Issue 39, 2010
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Recognition and regulation of unique nucleic acid structures by small molecules

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Abstract

DNA and RNA are both polymorphic. Depending on the sequences and environmental conditions, they could exist in a variety of secondary structures that play key roles in many biological processes. Recognition of these structures by small ligands is very important for the development of new drugs and new tools. In this article, we will focus on recent advances in the field of molecular recognition and regulation of small ligands with several unique nucleic acid structures, and we will also highlight some of their potential applications in medicinal chemistry and biotechnology.

Graphical abstract: Recognition and regulation of unique nucleic acid structures by small molecules

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Publication details

The article was received on 10 May 2010, accepted on 29 Jun 2010 and first published on 09 Aug 2010


Article type: Feature Article
DOI: 10.1039/C0CC01312A
Citation: Chem. Commun., 2010,46, 7283-7294
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    Recognition and regulation of unique nucleic acid structures by small molecules

    G. Song and J. Ren, Chem. Commun., 2010, 46, 7283
    DOI: 10.1039/C0CC01312A

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