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Issue 31, 2010
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Zeta potential based colorimetric immunoassay for the direct detection of diabetic marker HbA1c using gold nanoprobes

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Abstract

A one-step homogeneous colorimetric immunoassay format coupled with zeta potential measurements for determination of specific diabetic biomarker glycated hemoglobin (HbA1c) using functionalised gold nanoparticles as bioprobes is reported. The assay exhibited an excellent sensitivity based on absorbance and zeta potential measurements showing the dynamic response range from 0.001–0.004 mg mL−1 for HbA1c with a detection limit of 0.0015 mg mL−1.

Graphical abstract: Zeta potential based colorimetric immunoassay for the direct detection of diabetic marker HbA1c using gold nanoprobes

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Supplementary files

Article information


Submitted
04 Mar 2010
Accepted
27 May 2010
First published
23 Jun 2010

Chem. Commun., 2010,46, 5755-5757
Article type
Communication

Zeta potential based colorimetric immunoassay for the direct detection of diabetic marker HbA1c using gold nanoprobes

N. Wangoo, J. Kaushal, K. K. Bhasin, S. K. Mehta and C. R. Suri, Chem. Commun., 2010, 46, 5755
DOI: 10.1039/C0CC00224K

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