A novel electrochemical DNAzyme sensor for the amplified detection of Pb2+ ions

Xiaorong Yang; Juan Xu; Xuemei Tang; Huixiang Liu; Danbi Tian

doi:10.1039/C002137G

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A novel electrochemical DNAzyme sensor for the amplified detection ofPb²⁺ ions†

Xiaorong Yang,^a Juan Xu,^a Xuemei Tang,^a Huixiang Liu^a and Danbi Tian*^a

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* Corresponding authors

^a College of Science, Nanjing University of Technology, Nanjing 210009, PR China
E-mail: danbi@njut.edu.cn
Fax: +86 25 83587443
Tel: +86 25 83587428

Abstract

A novel amplification strategy based on DNAzyme functionalized gold nanoparticles was employed to enhance the sensitivity of an electrochemical sensor for detection of Pb²⁺. The detection limit is 0.028 nM, which is much lower than for other electrochemical DNAzyme sensors.

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Supplementary files

Experimental details, sensor preparation, TEM of AuNPs, and electrochemical studies PDF (983K)

Article information

DOI: https://doi.org/10.1039/C002137G
Article type: Communication
Submitted: 02 Feb 2010
Accepted: 19 Mar 2010
First published: 01 Apr 2010

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Chem. Commun., 2010,46, 3107-3109

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A novel electrochemical DNAzyme sensor for the amplified detection of Pb²⁺ ions

X. Yang, J. Xu, X. Tang, H. Liu and D. Tian, Chem. Commun., 2010, 46, 3107 DOI: 10.1039/C002137G

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Chemical Communications