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Issue 23, 2010
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Total synthesis of (+)-stachyflin: a potential anti-influenza A virus agent

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Abstract

The first enantioselective total synthesis of (+)-stachyflin, a potential anti-influenza A virus agent, was achieved; the method features a BF3·Et2O-induced domino epoxide-opening/rearrangement/cyclization reaction to stereoselectively form the requisite pentacyclic ring system in one step.

Graphical abstract: Total synthesis of (+)-stachyflin: a potential anti-influenza A virus agent

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Article information


Submitted
06 Jan 2010
Accepted
04 Mar 2010
First published
01 Apr 2010

Chem. Commun., 2010,46, 4055-4057
Article type
Communication

Total synthesis of (+)-stachyflin: a potential anti-influenza A virus agent

K. Watanabe, J. Sakurai, H. Abe and T. Katoh, Chem. Commun., 2010, 46, 4055
DOI: 10.1039/C000193G

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